| Dataset | RNR_GSEA_DESEQ2_PVAL |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | KEGG_CALCIUM_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.10040641 |
| Normalized Enrichment Score (NES) | -1.5377272 |
| Nominal p-value | 0.058027077 |
| FDR q-value | 0.5165855 |
| FWER p-Value | 0.995 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VDAC3 | 152 | 0.994 | -0.0025 | No | ||
| 2 | CAMK2B | 234 | 0.989 | -0.0011 | No | ||
| 3 | PPID | 317 | 0.983 | 0.0002 | No | ||
| 4 | CCKAR | 854 | 0.954 | -0.0231 | No | ||
| 5 | PLCG1 | 1035 | 0.946 | -0.0271 | No | ||
| 6 | PRKCB | 1137 | 0.940 | -0.0268 | No | ||
| 7 | EDNRB | 1147 | 0.939 | -0.0216 | No | ||
| 8 | VDAC1 | 1195 | 0.936 | -0.0184 | No | ||
| 9 | ATP2B4 | 1212 | 0.935 | -0.0135 | No | ||
| 10 | CACNA1F | 1219 | 0.934 | -0.0081 | No | ||
| 11 | CALM1 | 1285 | 0.930 | -0.0059 | No | ||
| 12 | CALML6 | 1353 | 0.927 | -0.0037 | No | ||
| 13 | TACR3 | 1417 | 0.924 | -0.0014 | No | ||
| 14 | PLCD4 | 1466 | 0.922 | 0.0017 | No | ||
| 15 | GRPR | 1717 | 0.908 | -0.0061 | No | ||
| 16 | RYR2 | 1758 | 0.906 | -0.0025 | No | ||
| 17 | HRH1 | 1760 | 0.905 | 0.0032 | No | ||
| 18 | SLC25A4 | 1833 | 0.902 | 0.0051 | No | ||
| 19 | PTK2B | 1876 | 0.899 | 0.0085 | No | ||
| 20 | CAMK2G | 2029 | 0.891 | 0.0060 | No | ||
| 21 | BST1 | 2172 | 0.884 | 0.0041 | No | ||
| 22 | ADORA2B | 2190 | 0.883 | 0.0089 | No | ||
| 23 | CACNA1S | 2313 | 0.877 | 0.0081 | No | ||
| 24 | ATP2B3 | 3062 | 0.835 | -0.0267 | No | ||
| 25 | CAMK2A | 3133 | 0.831 | -0.0248 | No | ||
| 26 | GNAQ | 3312 | 0.821 | -0.0287 | No | ||
| 27 | VDAC2 | 4399 | 0.763 | -0.0818 | No | ||
| 28 | AVPR1A | 4435 | 0.761 | -0.0779 | No | ||
| 29 | P2RX3 | 4496 | 0.758 | -0.0754 | No | ||
| 30 | ITPKB | 4509 | 0.757 | -0.0703 | No | ||
| 31 | RYR1 | 4604 | 0.751 | -0.0697 | No | ||
| 32 | ADRA1B | 4922 | 0.734 | -0.0811 | No | ||
| 33 | HRH2 | 5073 | 0.725 | -0.0835 | No | ||
| 34 | PHKB | 5106 | 0.723 | -0.0795 | No | ||
| 35 | MYLK | 5118 | 0.722 | -0.0743 | No | ||
| 36 | ERBB4 | 5136 | 0.720 | -0.0695 | No | ||
| 37 | CD38 | 5277 | 0.712 | -0.0713 | No | ||
| 38 | CHRM1 | 5414 | 0.705 | -0.0729 | No | ||
| 39 | CALM3 | 5496 | 0.701 | -0.0716 | No | ||
| 40 | TACR2 | 5568 | 0.697 | -0.0697 | No | ||
| 41 | CALM2 | 5650 | 0.693 | -0.0683 | No | ||
| 42 | ITPKA | 5655 | 0.693 | -0.0628 | No | ||
| 43 | EDNRA | 5656 | 0.693 | -0.0570 | No | ||
| 44 | LHCGR | 6208 | 0.664 | -0.0811 | No | ||
| 45 | PLN | 6294 | 0.659 | -0.0800 | No | ||
| 46 | PRKACG | 6310 | 0.658 | -0.0751 | No | ||
| 47 | ERBB2 | 6382 | 0.654 | -0.0732 | No | ||
| 48 | PHKA1 | 6420 | 0.652 | -0.0694 | No | ||
| 49 | HTR4 | 6432 | 0.652 | -0.0643 | No | ||
| 50 | ERBB3 | 6541 | 0.646 | -0.0644 | No | ||
| 51 | GNA11 | 6562 | 0.645 | -0.0597 | No | ||
| 52 | EGFR | 6586 | 0.643 | -0.0552 | No | ||
| 53 | PPP3CC | 6672 | 0.639 | -0.0541 | No | ||
| 54 | PLCB3 | 6674 | 0.639 | -0.0484 | No | ||
| 55 | P2RX7 | 7070 | 0.616 | -0.0640 | No | ||
| 56 | PHKA2 | 7151 | 0.612 | -0.0626 | No | ||
| 57 | ADCY7 | 7193 | 0.610 | -0.0591 | No | ||
| 58 | TBXA2R | 7230 | 0.608 | -0.0553 | No | ||
| 59 | F2R | 7662 | 0.586 | -0.0729 | No | ||
| 60 | SPHK1 | 7810 | 0.579 | -0.0751 | No | ||
| 61 | GRIN2D | 7888 | 0.574 | -0.0735 | No | ||
| 62 | LTB4R2 | 7949 | 0.571 | -0.0710 | No | ||
| 63 | CACNA1D | 8390 | 0.546 | -0.0891 | No | ||
| 64 | SPHK2 | 8487 | 0.540 | -0.0886 | No | ||
| 65 | PLCD1 | 8526 | 0.538 | -0.0849 | No | ||
| 66 | GRIN1 | 8551 | 0.537 | -0.0805 | No | ||
| 67 | HTR2C | 8645 | 0.531 | -0.0798 | No | ||
| 68 | PPP3CB | 8704 | 0.528 | -0.0771 | No | ||
| 69 | SLC8A3 | 8722 | 0.527 | -0.0723 | No | ||
| 70 | CALML3 | 8876 | 0.518 | -0.0749 | No | ||
| 71 | ADCY2 | 8979 | 0.512 | -0.0746 | No | ||
| 72 | NOS2 | 8986 | 0.512 | -0.0692 | No | ||
| 73 | CHRM5 | 8989 | 0.512 | -0.0636 | No | ||
| 74 | HTR6 | 9006 | 0.511 | -0.0587 | No | ||
| 75 | PLCB1 | 9123 | 0.504 | -0.0592 | No | ||
| 76 | P2RX1 | 9238 | 0.498 | -0.0597 | No | ||
| 77 | ADRB3 | 9260 | 0.497 | -0.0551 | No | ||
| 78 | PTGFR | 9526 | 0.483 | -0.0637 | No | ||
| 79 | ADRB2 | 9699 | 0.474 | -0.0672 | No | ||
| 80 | NTSR1 | 9883 | 0.462 | -0.0714 | No | ||
| 81 | CYSLTR1 | 9893 | 0.462 | -0.0662 | No | ||
| 82 | PTAFR | 9917 | 0.461 | -0.0616 | No | ||
| 83 | PRKCA | 9983 | 0.457 | -0.0594 | No | ||
| 84 | ADORA2A | 10028 | 0.454 | -0.0561 | No | ||
| 85 | DRD1 | 10127 | 0.449 | -0.0556 | No | ||
| 86 | PDGFRB | 10453 | 0.431 | -0.0675 | No | ||
| 87 | GRIN2A | 10465 | 0.430 | -0.0623 | No | ||
| 88 | CACNA1A | 10488 | 0.429 | -0.0578 | No | ||
| 89 | GNA15 | 10576 | 0.424 | -0.0567 | No | ||
| 90 | SLC8A2 | 10731 | 0.416 | -0.0593 | No | ||
| 91 | MYLK3 | 11392 | 0.380 | -0.0894 | No | ||
| 92 | RYR3 | 11597 | 0.369 | -0.0947 | Yes | ||
| 93 | TRHR | 11619 | 0.368 | -0.0900 | Yes | ||
| 94 | PDE1C | 11668 | 0.365 | -0.0869 | Yes | ||
| 95 | ATP2A3 | 11841 | 0.354 | -0.0905 | Yes | ||
| 96 | AGTR1 | 11890 | 0.350 | -0.0873 | Yes | ||
| 97 | BDKRB1 | 12028 | 0.343 | -0.0890 | Yes | ||
| 98 | PTGER1 | 12050 | 0.342 | -0.0844 | Yes | ||
| 99 | TNNC2 | 12068 | 0.341 | -0.0796 | Yes | ||
| 100 | SLC25A31 | 12175 | 0.334 | -0.0796 | Yes | ||
| 101 | PHKG2 | 12192 | 0.333 | -0.0747 | Yes | ||
| 102 | NOS3 | 12226 | 0.331 | -0.0707 | Yes | ||
| 103 | ATP2B1 | 12243 | 0.330 | -0.0658 | Yes | ||
| 104 | OXTR | 12260 | 0.329 | -0.0610 | Yes | ||
| 105 | PLCB4 | 12389 | 0.322 | -0.0622 | Yes | ||
| 106 | PPP3R2 | 12623 | 0.308 | -0.0690 | Yes | ||
| 107 | GNA14 | 12760 | 0.300 | -0.0707 | Yes | ||
| 108 | DRD5 | 12836 | 0.296 | -0.0690 | Yes | ||
| 109 | PLCZ1 | 12874 | 0.294 | -0.0652 | Yes | ||
| 110 | ATP2A1 | 12895 | 0.293 | -0.0606 | Yes | ||
| 111 | CAMK4 | 12940 | 0.290 | -0.0572 | Yes | ||
| 112 | ADCY1 | 13171 | 0.277 | -0.0639 | Yes | ||
| 113 | ATP2A2 | 13226 | 0.274 | -0.0611 | Yes | ||
| 114 | CHRNA7 | 13252 | 0.273 | -0.0567 | Yes | ||
| 115 | ADRB1 | 13366 | 0.266 | -0.0571 | Yes | ||
| 116 | HTR7 | 13416 | 0.264 | -0.0540 | Yes | ||
| 117 | PLCG2 | 13446 | 0.263 | -0.0498 | Yes | ||
| 118 | SLC25A5 | 13545 | 0.258 | -0.0494 | Yes | ||
| 119 | PTGER3 | 13548 | 0.257 | -0.0437 | Yes | ||
| 120 | PLCB2 | 13599 | 0.254 | -0.0407 | Yes | ||
| 121 | PRKX | 13766 | 0.244 | -0.0439 | Yes | ||
| 122 | AVPR1B | 13801 | 0.242 | -0.0400 | Yes | ||
| 123 | CHRM2 | 13835 | 0.240 | -0.0361 | Yes | ||
| 124 | PDGFRA | 13836 | 0.240 | -0.0303 | Yes | ||
| 125 | ADCY4 | 13886 | 0.237 | -0.0272 | Yes | ||
| 126 | P2RX5 | 13982 | 0.233 | -0.0266 | Yes | ||
| 127 | CHP2 | 14267 | 0.217 | -0.0363 | Yes | ||
| 128 | P2RX2 | 14501 | 0.204 | -0.0432 | Yes | ||
| 129 | PRKACA | 14503 | 0.204 | -0.0375 | Yes | ||
| 130 | CYSLTR2 | 14525 | 0.203 | -0.0328 | Yes | ||
| 131 | P2RX4 | 14533 | 0.202 | -0.0275 | Yes | ||
| 132 | CACNA1C | 14570 | 0.200 | -0.0237 | Yes | ||
| 133 | ADRA1D | 14716 | 0.193 | -0.0258 | Yes | ||
| 134 | ADCY9 | 14817 | 0.188 | -0.0255 | Yes | ||
| 135 | ITPR3 | 14856 | 0.186 | -0.0218 | Yes | ||
| 136 | SLC25A6 | 14884 | 0.184 | -0.0175 | Yes | ||
| 137 | GNAL | 14907 | 0.183 | -0.0129 | Yes | ||
| 138 | CCKBR | 14936 | 0.181 | -0.0087 | Yes | ||
| 139 | PDE1B | 15092 | 0.172 | -0.0114 | Yes | ||
| 140 | MYLK2 | 15096 | 0.171 | -0.0058 | Yes | ||
| 141 | CAMK2D | 15211 | 0.166 | -0.0062 | Yes | ||
| 142 | PRKCG | 15474 | 0.153 | -0.0146 | Yes | ||
| 143 | PLCD3 | 15523 | 0.150 | -0.0115 | Yes | ||
| 144 | PHKG1 | 15597 | 0.147 | -0.0097 | Yes | ||
| 145 | P2RX6 | 15604 | 0.146 | -0.0043 | Yes | ||
| 146 | PPP3CA | 15731 | 0.140 | -0.0054 | Yes | ||
| 147 | GRM5 | 15848 | 0.134 | -0.0059 | Yes | ||
| 148 | PPP3R1 | 15909 | 0.130 | -0.0034 | Yes | ||
| 149 | ADRA1A | 16067 | 0.120 | -0.0062 | Yes | ||
| 150 | CACNA1H | 16103 | 0.119 | -0.0023 | Yes | ||
| 151 | PRKACB | 16105 | 0.119 | 0.0034 | Yes | ||
| 152 | TACR1 | 16128 | 0.117 | 0.0079 | Yes | ||
| 153 | NOS1 | 16304 | 0.108 | 0.0042 | Yes | ||
| 154 | TNNC1 | 16504 | 0.098 | -0.0008 | Yes | ||
| 155 | ADCY3 | 16584 | 0.093 | 0.0006 | Yes | ||
| 156 | GNAS | 16602 | 0.093 | 0.0055 | Yes | ||
| 157 | ITPR1 | 16700 | 0.087 | 0.0059 | Yes | ||
| 158 | GRIN2C | 16867 | 0.079 | 0.0027 | Yes | ||
| 159 | ITPR2 | 16933 | 0.075 | 0.0049 | Yes | ||
| 160 | CACNA1I | 17035 | 0.070 | 0.0052 | Yes | ||
| 161 | CHRM3 | 17203 | 0.062 | 0.0019 | Yes | ||
| 162 | SLC8A1 | 17477 | 0.048 | -0.0071 | Yes | ||
| 163 | ATP2B2 | 17847 | 0.031 | -0.0214 | Yes | ||
| 164 | HTR2B | 17963 | 0.025 | -0.0219 | Yes | ||
| 165 | PLCE1 | 18050 | 0.021 | -0.0208 | Yes | ||
| 166 | ADCY8 | 18171 | 0.015 | -0.0215 | Yes | ||
| 167 | BDKRB2 | 18185 | 0.015 | -0.0165 | Yes | ||
| 168 | CACNA1G | 18307 | 0.010 | -0.0173 | Yes | ||
| 169 | HTR2A | 18317 | 0.009 | -0.0120 | Yes | ||
| 170 | TRPC1 | 18425 | 0.005 | -0.0121 | Yes | ||
| 171 | GRM1 | 18517 | 0.002 | -0.0113 | Yes | ||
| 172 | CACNA1E | 18533 | 0.002 | -0.0063 | Yes | ||
| 173 | CACNA1B | 18596 | 0.000 | -0.0040 | Yes | ||
| 174 | PDE1A | 18616 | 0.000 | 0.0008 | Yes |
